Original articleCentral Corneal Thickness in Adult South Indians: The Chennai Glaucoma Study
Section snippets
Methods
This study was approved by the institutional ethics review board. The methods and design of the Chennai Glaucoma Study are described in detail elsewhere.19 Briefly, the Chennai Glaucoma Study was designed to estimate the prevalence of glaucoma. A sample size of 4758 was arrived at assuming an 85% response rate for an assumed 3% population prevalence of glaucoma with a relative precision of 25% and a design effect of 2. Therefore, 4800 subjects each from the rural and urban populations were
Study Cohort
Nine thousand six hundred subjects were enumerated. Of them 7774 subjects (rural-to-urban ratio, 3924:3850) participated in the study. There was no difference between the urban and the rural groups in terms of gender distribution and participation and nonparticipation rates. However, the urban population was significantly older than the rural population, both among the participants (54.8±10.6 years vs. 53.8±10.6 years; P<0.0001) and nonparticipants (53.8±10.9 years vs. 52.5±10.5 years; P<0.008).
Discussion
This study reports the distribution and factors associated with CCT among individuals from a rural and an urban south Indian population. To the best of the authors' knowledge, this is the first population-based report of its kind from India. These findings suggest that females tend to have thinner corneas. Central corneal thickness negatively correlated with increasing age and positively with intraocular pressure. Past studies have shown there are ethnicity-related differences in the average
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Cited by (0)
Manuscript no. 2009-374.
Financial Disclosure(s): The author(s) have made the following disclosure(s):
Lingam Vijaya - Lecturer - Alcon, Pfizer, and Allergan.
Ronnie George - lecturer - Carl Zeiss, Pfizer, and Allergan.
Supported by the Chennai Willingdon Corporate Foundation, Chennai, India.