Original articlesDry eye in diabetic patients
Section snippets
Methods
The electronic medical records of all members (470,350 members) in the central district of the largest health maintenance organization (HMO) in Israel (Clalit Health Services) were followed prospectively between January 1 and December 31, 2003. All members older than 50 years on January 1, 2003, who did not terminate their membership during 2003 were included (159,634 members).
Of the 159,634 members, 22,382 (14%) were diabetic according to the Clalit Health Services diabetes registry. The
Results
Table 1 shows the characteristics of diabetic and nondiabetic members receiving ocular lubrication compared with all members in the district. The mean age of diabetic patients consuming ocular lubrication was slightly higher than that of the nondiabetic patients, as was the age of all diabetic patients compared with all nondiabetic patients in the district. More female than male members consumed lubrication, both in the diabetic group (male to female ratio 1:1.74) and the nondiabetic group
Discussion
We have shown that significantly more diabetic patients, of all age groups older than 50 years, consumed more ocular lubrication than nondiabetic patients. Dry eye can result from either interruption of the tearing reflex pathways or from any process that affects the ability of the lacrimal gland to secrete.14 In diabetes, it is possible that damage to the microvasculature of the lacrimal gland together with autonomic neuropathy may contribute to impaired function of the gland. Sensory
Dr. Igor Kaiserman M.D. M.Sc. MPA graduated cum-laude the Hebrew University in Jerusalem. Residency in ophthalmology at the Hadassah Medical Center. Lecturer in ophthalmology at the Hadassah College and head of several computers courses at the Hebrew University. Dr. Kaiserman’s research interests include uveal melanoma, refractive surgery and intercellular calcium signaling.
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2021, Primary Care DiabetesCitation Excerpt :Such variability may be caused by intervening factors as this syndrome suffers influence of patient’s age (being more common in those with older age); used medications (such as isotretinoin, tricyclic antidepressants, selective serotonin reuptake inhibitors, antihistamines), previous eye surgery (that damages tearing somatosensory reflex) [7] and, according to certain authors, diabetes control [5,6]. Kaiserman et al. [6] observed that poor glycemic control correlates with increased artificial tear use in diabetic patients. Animal studies showed that diabetic mice have significant decrease in aqueous tear production when compared to the non-diabetic ones [8].
Study of dry eye disease in type 2 diabetes mellitus and its association with diabetic retinopathy in Western India
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Dr. Igor Kaiserman M.D. M.Sc. MPA graduated cum-laude the Hebrew University in Jerusalem. Residency in ophthalmology at the Hadassah Medical Center. Lecturer in ophthalmology at the Hadassah College and head of several computers courses at the Hebrew University. Dr. Kaiserman’s research interests include uveal melanoma, refractive surgery and intercellular calcium signaling.