Original articleOphthalmic imaging by spectral optical coherence tomography☆
Section snippets
Methods
The SOCT instrument is based on an open-air Michelson interferometer set-up. Two types of light sources are used in the experiments presented here. For high-resolution images, a pulse train from a home-built femtosecond Ti:Sapphire laser (4-nJ pulse energy, 80-MHz repetition rate, 40-nm full-width-half-maximum (FWHM) spectrum centered at a wavelength of 830 nm) is employed. The pulses are first compressed in a standard, double SF10 prism compressor, attenuated to approximately 2 nJ with a
Fast, high-resolution soct
Fast in vivo ophthalmic SOCT imaging with a broadband light beam generated in a photonic fiber is demonstrated in a normal human subject. Each A-scan is recorded during 128 μs and processed to yield a single line in a cross-sectional image. High resolution renders the images of a layered structure sharp and also provides the opportunity to locate and observe details at micrometer resolution.
A high resolution and high-speed SOCT horizontal cross-sectional image of the macular region of the human
Discussion
It is a well-established fact that an ultra-high resolution time domain OCT system provides unique information about ocular structures which, in the past, was only accessible by means of histology. As a result of its short acquisition time and high sensitivity,12 SOCT only needs to use a much lower exposure/A-scan to realize images of quality comparable to those obtained by traditional time domain OCT. It has also been employed to obtain functional information on retinal blood flow.13, 14 The
Supplementary files
Acknowledgements
This work was supported by Grant KBN 4T11E023 22, and an FNP′2003 Scholarship for Young Researchers.
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