Automated scanning laser ophthalmoscope image montages of retinal diseases☆
Section snippets
Confocal scanning laser ophthalmoscopy
The confocal laser scanning ophthalmoscope images the retina in three dimensions and has been described previously by our group.3, 4 A small pinhole aperture located in a plane conjugate to the focus plane allows imaging of “optical slices” of the retina; this technique is called confocal imaging or imaging in a tightly confocal mode.5 We have previously described the use of this technology for examination of the macula, optic nerve head, and angiography.6 The confocal SLO largely discriminates
Results
The results of this study are summarized in Table 1. Twelve eyes of 8 patients were imaged using fluorescein angiography, 488-nm illumination, and filter cutoff at 500 nm Figure 2, Figure 3. Eight eyes of five patients were imaged using infrared light, 840 nm Figure 4, Figure 5, Figure 6. Two eyes of two patients were imaged using ICG angiography, 795-nm wavelength that provided illumination to excite the ICG dye, which fluoresces at 835 nm (Fig 7), and eight eyes of six patients using red-free
Discussion
Automated fundus montage synthesis provides an accurate way to evaluate the entire fundus with high resolution as well as to localize an area of interest. Zooming increases the magnification, providing details of the entire fundus without loss of resolution, a fact that cannot be achieved with a fundus camera. In this way, we can obtain global information about the image and local information about a single feature. The depth of focus of fundus cameras is great enough to encompass the entire
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Bilateral chorioretinal coloboma discovered with ultra-wide field retinal imaging
2012, Journal of OptometryCitation Excerpt :The green laser (532 mm) images mainly the sensory retina and pigment epithelium, while the red laser (633 mm) images mainly deeper structures of the retina, from the pigment epithelium to the choroid. The advantage of this system is that it allows the retina to be scanned over a large portion of the ocular fundus with a field of up to 200° without pupil dilation, as opposed to the view with a standard fundus camera of only 45° and that of an SLO of 20–60°.13–15 The exam involves asking the patient to focus on a target in the instrument and takes less than one minute for each eye to position the patient and capture the image.
Feature-based retinal image registration by enforcing transformation-guided and robust estimation
2017, Proceedings - 2017 International Conference on Green Informatics, ICGI 2017
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Supported by National Eye Institute EY07366, Bethesda, Maryland; Research to Prevent Blindness Inc., New York, New York; and the Whitaker Foundation, Rosslyn, Virginia, Biomedical Engineering Research Grant. Dr. William R. Freeman is the recipient of the RPB Lew Wasserman Award.