Water properties of hydrogel contact lens materials: a possible predictive model for corneal desiccation staining
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Pharmaceutical-loaded contact lenses as an ocular drug delivery system: A review of critical lens characterization methodologies with reference to ISO standards
2021, Contact Lens and Anterior EyeCitation Excerpt :SCL dehydration can lead to several problems, such as: changes in lens parameters (e.g., diameter, sagittal depth and base curve) [94,95], and changes in oxygen [96,97] and ionic permeability [98]. The amount of dehydration and the time to reach equilibrium are influenced by several elements, including: the maximum water content of the polymer [99,100], the lens thickness [94,98,99,101], the temperature and relative humidity [95], and also the volume and tonicity (i.e. salt-uptake ability of a solution) of the wearers’ tears [102,103]. The standard method for determining the water content of tested specimens is a gravimetric method utilizing loss on drying using an oven [38,104].
Contact Lens Complications
2018, Contact Lens ComplicationsHow the structural and physicochemical properties of polyacrylamide/alginate hydrogel influence its oxygen permeability
2016, Polymer TestingCitation Excerpt :It can be assumed that the discrepancies observed in the values of the water properties among the materials tested in this study are meaningful. However, it’s worth noting that the heat of fusion of pure water, used for the calculation of the amounts of free water, is higher than that of the water melting below 0 °C, leading consequently to a slight overestimation of the amount of bound water [6]. It was observed in the Fig. 4 that the amount of non-bound or “free water” increased linearly (R2 = 0.89) with the total water content of the hydrogel but inversely (R2 = 0.84) to the network density.
Effect of water content on microstructures and oxygen permeation in PSiMA-IPN-PMPC hydrogel: A molecular simulation study
2012, Chemical Engineering ScienceCitation Excerpt :For hydrogel lenses, many of their physicochemical properties are governed by the state of water. It has been revealed that hydrogels containing a larger proportion of free water tend to induce corneal desiccation more readily than those containing a larger proportion of bound water (Mirejovsky et al., 1993). A marked facilitation of oxygen transport was observed in P(VP–co–HEMA) hydrogel lens that contains more free water (Wang et al., 2008).
Post-lens tear-film depletion due to evaporative dehydration of a soft contact lens
2006, Journal of Membrane ScienceDynamic wettability properties of a soft contact lens hydrogel
2005, Colloids and Surfaces B: Biointerfaces